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| The good | |
 | Vash is a legend in his own time. Tales of him slaying a hundred people at the blink of an eye have people so nervous, there is a $$60,000,000,000 (that's right, sixty billion double dollars) bounty on his head, despite there being no hard-proof of his killing a single person. Word of his arrival proceeds him wherever he goes, though the tales of him have his description so distorted that no one recognizes him as the $60,000,000,000 man. Unlike the stories, Vash is less of a womanizer and more of a plain pervert. He is fairly clumsy, and it is unclear whether he is talented or just very lucky. |
 | Meryle-She is introduced as an insurance salesperson. In the beginning, she is anoyed at Vash 1: because he claims to be Vash, and she sees this as far-fetched, and 2:because he can be an irritating person. She warms up to him, though, as the series progresses and eventually falls in love with the wanted man. |
 | Millie-One word: Ditz. She is Meryle's partner, (ergo also an insurance lady) but is very trusting. She takes Vash at his word about his true identity from the beginning. Despite her happy-go-lucky additude, she packs a pretty serious gun, and isn't afraid to use it. This is one blonde you don't want to get on the wrong side of. |
| The Bad | |
 | Stan-Although he only appears in one episode, he is a rather nasty person. His past catches up with him in the end, and he stripped of his sherriff status. |
 | Just like stan, he is a "retired" bandit. He hepled take over a town that once thrived, and let it fall back into a dusty mess again. His past catches up with him, and he gets shot for it. |
 | not an important character, but in the first episode he is mistaken for Vash by the insurance ladies. I just thought his retractable giant steel boomerang was intersting, though. |
| The Strange | |
 | A mysterious feline that averages one brief appearence each episode. Naturally, this cryptic cat has a cult following. |